IL-31 Protein activates STAT3, potentially STAT1 and STAT5, through the IL31 receptor. It enhances myeloid progenitor cell survival and induces RETNLA and serum amyloid A protein expression in macrophages. IL-31 Proteins diverse functions suggest its importance in biological processes and potential implications in immune regulation and cell survival. IL-31 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-31 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 17.1 kDa, based on SDS-PAGE under reducing conditions.