BMPR1A/ALK-3, Mouse (HEK293, His-Fc)

Artikelnummer: MCE-HY-P7483
Artikelname: BMPR1A/ALK-3, Mouse (HEK293, His-Fc)
Artikelnummer: MCE-HY-P7483
Hersteller Artikelnummer: HY-P7483
Alternativnummer: MCE-HY-P7483-10UG,MCE-HY-P7483-50UG
Hersteller: MedchemExpress
Kategorie: Proteine/Peptide
Alternative Synonym: BMPR1A/ALK-3 Protein, Mouse (HEK293, His-Fc),Mouse,HEK293
BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues[1]. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis[2][3]. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders[4]. Mouse BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Mouse (HEK293, His-Fc) is produced in HEK293 cells and has 129 amino acids (Q24-R152), with C-terminal Fc and His-tags.
Molekulargewicht: 55-60 kDa
Reinheit: 98
Formel: 12166(Gene_ID)P36895 (Q24-R152)(Accession)
Anwendungsbeschreibung: MCE Product type: Recombinant Proteins