BMPR1A/ALK-3, Human (HEK293, Fc-His)

Produktübersicht

• Artikelname: BMPR1A/ALK-3, Human (HEK293, Fc-His)
• Artikelnummer: MCE-HY-P7484
• Hersteller Artikelnummer: HY-P7484
• Alternativnummer: MCE-HY-P7484-10UG,MCE-HY-P7484-50UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: BMPR1A/ALK-3 Protein, Human (HEK293, Fc-His),Human,HEK293

Produktbeschreibung

BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues[1]. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis[2][3]. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders[4]. Human BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Human (HEK293, Fc-His) is produced in HEK293 cells and has 129 amino acids (Q24-R152), with C-terminal Fc and His-tags.

Produkteigenschaften

• Molekulargewicht: Approximately 60.0 kDa
• Reinheit: 95
• Formel: 657(Gene_ID)P36894 (Q24-R152)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins