The ECE-2 protein plays a crucial role in vascular regulation by catalyzing the conversion of large endothelin-1 to endothelin-1, helping to regulate blood pressure and vascular tone. Furthermore, ECE-2 exhibits potential methyltransferase activity and may be involved in amyloid-beta processing, suggesting that this enzyme has a broader impact on cellular function than its established role in endothelin processing. ECE-2 Protein, Human (HEK293, His) is the recombinant human-derived ECE-2 protein, expressed by HEK293 , with N-His labeled tag.
Molekulargewicht:
Approximately 120-125 kDa due to the glycosylation.