Ebola virus Glycoprotein/GP (QDA39862, HEK293, His)

Artikelnummer: MCE-HY-P75268
Artikelname: Ebola virus Glycoprotein/GP (QDA39862, HEK293, His)
Artikelnummer: MCE-HY-P75268
Hersteller Artikelnummer: HY-P75268
Alternativnummer: MCE-HY-P75268-20UG,MCE-HY-P75268-5UG,MCE-HY-P75268-50UG,MCE-HY-P75268-10UG
Hersteller: MedchemExpress
Kategorie: Proteine/Peptide
Alternative Synonym: Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His),Virus,HEK293
Ebola virus Glycoprotein/GP Protein is pivotal in viral entry, serving as the receptor-binding subunit.In later infection stages, GP1 down-regulates crucial host cell surface molecules, including integrins like ITGA1-6, disrupting adhesion and potentially causing blood vessel integrity disruption.GP1 interacts with host TLR4, stimulating monocyte differentiation, leading to T-lymphocyte bystander death.It down-regulates natural killer cell function, counters BST2/tetherin, cooperates with VP40 for NF-kappa-B activation, acts as an antibody decoy, and induces cytokine transcription in host macrophages and dendritic cells through TLR4 activation.Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His) is the recombinant Virus-derived Ebola virus Glycoprotein/GP protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht: 92-120&23-25 kDa
Reinheit: 90
Formel: /(Gene_ID)QDA39862 (M1-Q650)(Accession)
Anwendungsbeschreibung: MCE Product type: Recombinant Proteins