Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His),Virus,HEK293
Ebola virus Glycoprotein/GP Protein is pivotal in viral entry, serving as the receptor-binding subunit.In later infection stages, GP1 down-regulates crucial host cell surface molecules, including integrins like ITGA1-6, disrupting adhesion and potentially causing blood vessel integrity disruption.GP1 interacts with host TLR4, stimulating monocyte differentiation, leading to T-lymphocyte bystander death.It down-regulates natural killer cell function, counters BST2/tetherin, cooperates with VP40 for NF-kappa-B activation, acts as an antibody decoy, and induces cytokine transcription in host macrophages and dendritic cells through TLR4 activation.Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His) is the recombinant Virus-derived Ebola virus Glycoprotein/GP protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
92-120&23-25 kDa
Reinheit:
90
Formel:
/(Gene_ID)QDA39862 (M1-Q650)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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