The B7-H4 protein acts as a negative regulator, inhibiting T cell activation, proliferation, cytokine production, and cytotoxicity. When expressed on tumor macrophages, it cooperates with regulatory T cells (Tregs) to suppress tumor-associated antigen-specific T cell immunity and create an immunosuppressive microenvironment. B7-H4 Protein, Rat (HEK293, His) is the recombinant rat-derived B7-H4 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 42-65 kDa due to the glycosylation.
Reinheit:
95
Formel:
295322(Gene_ID)Q501W4 (F29-S256)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
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