4-1BB (CD137, TNFRSF9), is a surface glycoprotein, a receptor of TNFSF9/4-1BBL, belongs to the tumor necrosis factor (TNF) receptor superfamily[1]. 4-1BB is helpful for T cell activation and development, and also induces peripheral mononuclear cell proliferation and migration to the tumor microenvironment[2]. 4-1BB is also involved in enhancing Nrf2 and NF-kappaB pathway mediated apoptosis of endothelial cells[3]. CD137/4-1BB Protein, Canine (HEK293, His) has 185 amino acids (M1-S185), produced by HEK293 cells with C-terminal His-tag.
Molekulargewicht:
Approximately 24-34 kDa
Reinheit:
95.70
Formel:
608274(Gene_ID)XP_850336.1 (I24-S185)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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