Fc gamma RIIIA/CD16a Protein, Rat (HEK293, His),Rat,HEK293
Fc gamma RIIIA/CD16a is a receptor for the invariant Fc fragment of immunoglobulin gamma (IgG). Fc gamma RIIIA/CD16a regulates NK cell survival and proliferation and prevents NK cell progenitor cell apoptosis. Fc gamma RIIIA/CD16a plays a role in mediating the anti-tumor activity of therapeutic antibodies by triggering TNFA-dependent ADCC, which promotes the entry of the virus into bone marrow cells during secondary infection and subsequent viral replication through antibody-dependent enhancement (ADE). Fc gamma RIIIA/CD16a Protein, Rat (HEK293, His) is the recombinant rat-derived Fc gamma RIIIA/CD16a, expressed by HEK293, with C-His labeled tag.
