IFN-gamma R1/CD119, Rat (HEK293, Fc)

Produktübersicht

• Artikelname: IFN-gamma R1/CD119, Rat (HEK293, Fc)
• Artikelnummer: MCE-HY-P75824
• Hersteller Artikelnummer: HY-P75824
• Alternativnummer: MCE-HY-P75824-100UG,MCE-HY-P75824-50UG,MCE-HY-P75824-10UG,MCE-HY-P75824-2UG,MCE-HY-P75824-500UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: IFN-gamma R1/CD119 Protein, Rat (HEK293, Fc),Rat,HEK293

Produktbeschreibung

IFN-gamma R1 (CD119), one of the subunit of IFN-gamma receptor, is a receptor for IFN-gamma. IFN-gamma R1 forms the functional receptor with IFN-gamma R2. Upon binding with IFN-gamma, IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1]. Then, JAK1 and JAK2 are phosphorylated and activated, and STAT1 is recruited to the receptor complex. Phosphorylated STAT1 translocates to the nucleus, where it regulates the expression of IFN-responsive genes (e.g. CD54)[2]. IFN-gamma R1/CD119 Protein, Rat (HEK293, Fc) is a recombinant mouse IFN-gamma R1 (M1-S241) with C-terminal hFc tag, which is produced in HEK293 cells.

Produkteigenschaften

• Molekulargewicht: 65-90 kDa
• Reinheit: 95.00
• Formel: 116465(Gene_ID)Q6P6T3 (A17-S241)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins