IL-18R alpha, Human (HEK293, His) Preis auf Anfrage
Artikelnummer:
MCE-HY-P75843
Hersteller Artikelnummer:
HY-P75843
Alternativnummer:
MCE-HY-P75843-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Proteine/Peptide
Alternative Synonym:
IL-18R alpha Protein, Human (HEK293, His),Human,HEK293
IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor alpha (Ralpha) and beta (Rbeta) chains at the plasma membrane, which induces multiple inflammatory cytokines[1]. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kbeta- inducing kinase, with subsequent activation of nuclear factor kbeta[2]. IL-18R alpha inhibits the production of IFN-gamma stimulated with the combination of rhIL-2 and rhIL-18[3]. IL-18R alpha Protein, Human (HEK293, His) is a recombinant protein with a His label that consists of 311 amino acids (A19-R329) and is produced by HEK293 cells.
Molekulargewicht:
Approximately 59.8 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formel:
8809(Gene_ID)Q13478 (A19-R329)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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