AITRL/TNFSF18, Human (HEK293, Fc) Preis auf Anfrage
Artikelnummer:
MCE-HY-P76110
Hersteller Artikelnummer:
HY-P76110
Alternativnummer:
MCE-HY-P76110-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Proteine/Peptide
Alternative Synonym:
AITRL/TNFSF18 Protein, Human (HEK293, Fc),Human,HEK293
AITRL, a type II transmembrane protein, is a ligand for glucocorticoid-induced TNFR-related protein (GITR). When AITRL binds to GITR, GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions. GITR/AITRL interaction plays a role in the pathogenesis of tumor, inflammation, as well as autoimmune diseases[1]. Besides, AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1, ICAM-1)[2]. AITRL/TNFSF18 Protein, Human (HEK293, Fc) is a recombinant human AITRL (Q72-S199) with C-terminal mFc tag, which is expressed in HEK293.
Molekulargewicht:
Approximately 45.5 kDa, based on SDS-PAGE under reducing conditions.
