BMPR1B/ALK-6 protein is a type I member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases[1]. BMPR1B/ALK-6 is the receptor for BMP-7/OP-1 and GDF-5, positively regulates chondrocyte differentiation through GDF-5 interaction[2][3]. BMPR1B/ALK-6 also involves in SCUBE3/BMP-2/BMP-4 signals regulation, controlling growth, morphogenesis, and bone and teeth development[4]. ALK-6/GDF-9/BMP-15 signals is essential in prolificacy of goat[5]. The mouse BMPR1B/ALK-6 protein contains 502 amino acids and a transmembrane domain (127-148 a.a.). BMPRIB/ALK-6 Protein, Mouse (HEK293, Fc) is produced by HEK293 cells (K14-K126) with C-terminal hFc-tag.
Molekulargewicht:
Approximately 39.4 kDa.
Reinheit:
96.00
Formel:
12167(Gene_ID)P36898 (K14-K126)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
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