FGFR2, also known as CD332 (differentiated cluster 332), is a receptor for fibroblast growth factor. FGFR2 is involved in activation of RAS, MAPK1/ERK2, MAPK3/ERK1, MAP kinase signaling pathways, and AKT1 signaling pathways. FGFR2 up-regulates PAI-1 via JAK2/STAT3 signaling and induces M2 polarization in colorectal cancer macrophages. FGFR-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived FGFR-2 protein, expressed by HEK293 , with C-hFc labeled tag.
Molekulargewicht:
Approximately 89.9 kDa,based on SDS-PAGE under reducing conditions.
Formel:
14183(Gene_ID)E9Q5C3 (R22-E263)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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