BTLA/CD272 Protein, expressed on lymphocytes, is a negative regulator of antigen receptor signaling. Interacting with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, it modulates immune responses and maintains lymphocyte homeostasis. BTLA engages in cis and trans interactions with TNFRSF14, cis interactions regulate naive T cells, inhibiting trans interactions to maintain a resting state. During adaptive immune responses, predominant trans interactions provide survival signals to effector T cells. The intricate interplay highlights BTLAs multifaceted role in immune regulation. BTLA/CD272 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived BTLA/CD272 protein, expressed by HEK293 , with C-hFc labeled tag.
Molekulargewicht:
Approximately 41.4 kDa.
Formel:
/(Gene_ID)EHH16054 (K31-L155)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
