The Draxin protein is critical in commissural development in the spinal cord and forebrain, serving as a chemical pulse guidance protein for commissural axons. It inhibits dorsal spinal cord neurite outgrowth and acts as a Wnt signaling antagonist by interacting with LRP6, inhibiting cytosolic beta-catenin stabilization. Draxin Protein, Human (HEK293, His) is the recombinant human-derived Draxin protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 50-60 kDa due to the glycosylation
Reinheit:
95.00
Formel:
374946(Gene_ID)Q8NBI3 (G26-V349)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
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