IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1alpha, IL-1beta, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM)[1]. IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-kappaB and MAPK pathway[4]. IL-1R1 Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus extracellular region of IL-1R1 (M1-T332) with a C-Terminal His tag, which is produced in HEK293 cells.
Molekulargewicht:
Approximately 47-75 kDa
Reinheit:
96.30
Formel:
711726(Gene_ID)F7GVA6 (D21-T332)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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