Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation[1]. NGF-NGFR cascade activates NF-kappaB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells[3]. NGFR Protein, Mouse (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 243 amino acids (M1-N243) and is produced in HEK293 cells.
Molekulargewicht:
Approximately 43-60 kDa due to the glycosylation.
Reinheit:
97.30
Formel:
18053(Gene_ID)Q9Z0W1 (K32-N253)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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