PBK/TOPK Protein, Human (sf9, His),Human,Sf9 insect cells
PBK/TOPK Protein, a mitosis-specific kinase, phosphorylates MAP kinase p38, emphasizing its specific role in cell division. Implicated in lymphoid cell activation, PBK/TOPK has broader impacts on immune responses. When phosphorylated, it forms a complex with TP53, destabilizing TP53 and dampening the G2/M checkpoint in doxorubicin-induced DNA damage, highlighting its multifaceted functions in cell cycle control and genotoxic stress responses. PBK/TOPK Protein, Human (sf9, His) is the recombinant human-derived PBK/TOPK protein, expressed by Sf9 insect cells , with C-His labeled tag.
Molekulargewicht:
35-45 kDa
Reinheit:
95.00
Formel:
55872(Gene_ID)Q96KB5-1 (M1-V322)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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