IFN-alpha/beta R2, Cynomolgus (HEK293, His)

Produktübersicht

• Artikelname: IFN-alpha/beta R2, Cynomolgus (HEK293, His)
• Artikelnummer: MCE-HY-P77392
• Hersteller Artikelnummer: HY-P77392
• Alternativnummer: MCE-HY-P77392-50UG,MCE-HY-P77392-20UG,MCE-HY-P77392-100UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: IFN-alpha/beta R2 Protein, Cynomolgus (HEK293, His),Cynomolgus,HEK293

Produktbeschreibung

IFN-alpha/beta R2, one of the subunit of IFN-alpha/beta receptor, is a type I IFN receptor. IFN-alpha/beta R2 forms the heterodimeric receptor with IFNAR1, and binds to type I IFNs[1]. IFN-alpha/beta R2 also interacts with JAK1 and leads to tyrosine phosphorylation of the IFNARs and STAT proteins[2]. Upon activation by these IFNs, IFNAR1 and IFN-alpha/beta R2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2[3]. IFN-alpha/beta R2 Protein, Cynomolgus (HEK293, His) is a recombinant biotinylated cynomolgus IFN-alpha/beta R2 (M1-K243) with C-terminal His tag, which is produced in HEK293 cells.

Produkteigenschaften

• Molekulargewicht: Approximately 43-60 kDa, due to the glycosylation
• Reinheit: 98
• Formel: /(Gene_ID)EHH53981.1 (I27-K243)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins