IL-12 beta Protein, also known as natural killer cell stimulatory factor 2, is a common subunit (p40) of IL-12 and IL-23. IL-12 is a inflammatory factor expressed by activated macrophages, and involves in Th1-type immune response against cancer[1]. IL-12 beta Protein located outside the cell membrane, involves in singalling mediated by Jak-STAT[3]. IL-12 beta Protein consists of 335 amino acids (M1-N328) with a fibronectin type-III domain (233-324 a.a). IL-12 beta Protein, Marmoset is produced in HEK293 cells with a C-Terminal hFc-tag.
Molekulargewicht:
Approximately 75 kDa, based on SDS-PAGE under reducing conditions.
Reinheit:
98
Formel:
/(Gene_ID)F7IQ84 (I23-N328)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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