SIRP gamma Protein, a member of signal-regulatory protein (SIRP) family, is the only SIRP detected on T cells and activated NK cells. SIRP gamma can bind CD47, providing T cells and NK cells with a cell surface molecule capable of interacting with CD47. SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact, enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion. SIRP gamma Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived SIRP gamma protein, expressed by HEK293 , with C-hFc labeled tag.
Molekulargewicht:
Approximately 69-79 kDa,based on SDS-PAGE under reducing conditions.
Formel:
716034(Gene_ID)XP_028684116 (E29-H360)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
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