TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-alpha). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is expressed by HEK293 and has a transmembrane region (M1-D257) with hFc tag at the C-terminus[1].
Molekulargewicht:
Approximately 68 kDa,based on SDS-PAGE under reducing conditions.
