L-36R is a member of the IL-1 receptor family that contains six receptor proteins that form four signaling complexes: IL-1RI, IL-18R, IL-33R, and IL-36R, and two decoy receptors and two negative regulators. IL-36R is a heterodimer that consists of a receptor subunit named IL-1Rrp2 (IL-1RL2) and a co-receptor subunit Interleukin-1 receptor accessory protein, IL-1RAcP. The receptor can recognize three different agonists, IL-36alpha, IL-36beta, and IL-36gamma (also known as IL-1F6, IL-1F8, and IL-1F9), to induce the expression of inflammatory cytokines[1][2]. IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-1 Rrp2/IL-1 R6 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
60-70 kDa
Reinheit:
95
Formel:
/(Gene_ID)EHH61702.1 (D20-R335)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
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