LDLR Protein plays a pivotal role in cholesterol homeostasis, binding to LDL and mediating cellular uptake through endocytosis. Clustering into clathrin-coated pits is essential for internalization. In microbial infection, LDLR acts as a receptor for hepatitis C virus in hepatocytes, emphasizing its dual functionality in cholesterol metabolism and the cellular response to viral infections. LDLR Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived LDLR protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 115-130 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
