Kremen-2 protein is a receptor for Dickkopf protein and cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting LRP5 and LRP6 endocytosis. Its role in limb development ensures correct patterning and negatively affects bone formation. Kremen-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kremen-2 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 50-60 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formel:
73016(Gene_ID)Q8K1S7 (G25-S363)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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