The LRP-5 protein functions as a coreceptor, cooperating with Frizzled receptors to initiate the canonical Wnt signaling pathway. It is critical for cell fate determination and self-renewal and plays an important role in posterior ectoderm patterning during gastrulation and bone development by affecting osteoblast proliferation and differentiation. LRP-5 Protein, Human (HEK293, mFc) is the recombinant human-derived LRP-5 protein, expressed by HEK293 , with C-mFc labeled tag.
Molekulargewicht:
110-115 kDa
Reinheit:
95
Formel:
4041(Gene_ID)O75197 (E644-Q1263)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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