TNF-alpha/TNFSF2, Human (Biotinylated, HEK293, His-Avi)

Produktübersicht

• Artikelname: TNF-alpha/TNFSF2, Human (Biotinylated, HEK293, His-Avi)
• Artikelnummer: MCE-HY-P78218
• Hersteller Artikelnummer: HY-P78218
• Alternativnummer: MCE-HY-P78218-50UG,MCE-HY-P78218-20UG,MCE-HY-P78218-100UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: TNF-alpha/TNFSF2 Protein, Human (Biotinylated, HEK293, His-Avi),Human,HEK293

Produktbeschreibung

Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1]. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death[2]. TNF alpha stimulates NF-kappaB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-alpha MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3]. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4]. TNF-alpha/TNFSF2 Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant protein with C-Terminal Avi and His label, It consists of 157 amino acids (V77-L233) and is produced in HEK293 cells.

Produkteigenschaften

• Molekulargewicht: Approximately 21-24 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
• Reinheit: 95.00
• Formel: 7124(Gene_ID)P01375 (V77-L233)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins