CD40L/CD154/TRAP Trimer, Mouse (HEK293, Fc)

Produktübersicht

• Artikelname: CD40L/CD154/TRAP Trimer, Mouse (HEK293, Fc)
• Artikelnummer: MCE-HY-P78271
• Hersteller Artikelnummer: HY-P78271
• Alternativnummer: MCE-HY-P78271-20UG,MCE-HY-P78271-50UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: CD40L/CD154/TRAP Trimer Protein, Mouse (HEK293, Fc),Mouse,HEK293

Produktbeschreibung

CD40L (CD154, TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1]. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-kappaB/MAPK pathway[2][3]. CD40L also involves in B cell differentiation, maturation, and apoptosis[4]. CD40L in mouse, cleaved into 2 chains of membrane form (1-260 a.a.) and soluble form (112-260 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Trimer Protein, Mouse (HEK293, Fc) has a total length of 149 amino acids (M112-L260), is expressed in HEK392 cells with N-terminal hFc-tag.

Produkteigenschaften

• Molekulargewicht: 68-80 kDa
• Reinheit: 95
• Formel: 21947(Gene_ID)P27548 (M112-L260)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins