TRAIL R2/TNFRSF10B protein is the receptor of TNFSF10/TRAIL and activates apoptosis through FADD-mediated recruitment of caspase-8 to form death-inducing signaling complex (DISC).It initiates caspase cascade-mediated apoptosis and promotes NF-kappa-B activation, which is critical for ER stress-induced apoptosis.TRAIL R2/TNFRSF10B Protein, Mouse (HEK293, His) TRAIL R2/TNFRSF10B Protein, Mouse (HEK293, His) is the recombinant mouse-derived TRAIL R2/TNFRSF10B protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 30-40 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formel:
21933(Gene_ID)Q9QZM4 (N53-K180)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
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