HHLA2 protein, a key immune regulator, interacts with TMIGD2, providing crucial costimulation for T-cells during TCR-mediated activation. This interaction amplifies T-cell proliferation and cytokine production through an AKT-dependent signaling cascade, revealing HHLA2s role in enhancing T-cell responses and immune modulation. HHLA2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived HHLA2 protein, expressed by HEK293 , with C-His labeled tag. The total length of HHLA2 Protein, Cynomolgus (HEK293, His) is 325 a.a., with molecular weight of 60-70 kDa.
Molekulargewicht:
Approximately 60-70 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Formel:
/(Gene_ID)XP_005548285.1 (I21-N345)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
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