DKK-3 Protein, Human (R335G, HEK293, His),Human,HEK293
DKK-3 protein antagonizes canonical Wnt signaling by blocking LRP5/6-Wnt interactions and forming a ternary complex with KREMEN, thereby promoting LRP5/6 internalization.In vertebrate development, DKK-3, together with other DKKs, critically inhibits Wnt-regulated processes such as axial patterning, limb development, somitogenesis, and eye formation.DKK-3 Protein, Human (R335G, HEK293, His) is the recombinant human-derived DKK-3 protein, expressed by HEK293 , with C-6*His labeled tag and R335G, , , , mutation.
Molekulargewicht:
50-66 kDa
Reinheit:
99.00
Formel:
27122(Gene_ID)Q9UBP4 (A22-I350, R335G)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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