IFN-alpha/beta R2 protein and IFNAR1 together constitute the heterodimeric receptor of type I interferon and initiate the JAK-STAT signaling cascade. Upon binding of type I interferons, IFNAR1 and IFNAR2 activate related Janus kinases (TYK2 and JAK1) in proximity, resulting in cross-phosphorylation. IFN-alpha/beta R2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IFN-alpha/beta R2 protein, expressed by HEK293 , with C-6*His labeled tag.
Molekulargewicht:
Approximately 37-57 kDa
Reinheit:
98
Formel:
15976(Gene_ID)O35664-1 (S22-A242)(Accession)
Anwendungsbeschreibung:
Recombinant Proteins
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