Frizzled-9 is a WNT2 receptor that is critical for activation of the beta-catenin pathway, involved in Disheveled protein activation, GSK-3 kinase inhibition, nuclear beta-catenin accumulation, and Wnt target gene activation. In addition to classical signaling, it negatively regulates acetylcholine receptor clustering in neuromuscular junction assembly and affects the viability of neural progenitor cells by regulating the cell cycle. Frizzled-9 Protein, Mouse (HEK293, mFc) is the recombinant mouse-derived Frizzled-9 protein, expressed by HEK293 , with C-mFc labeled tag.
Molekulargewicht:
52-61 kDa
Reinheit:
96.73
Formel:
14371(Gene_ID)Q9R216 (L24-D186)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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