HRP-conjugated Anti-Mouse lgG is a conformation-specific secondary antibody that binds exclusively to native, non-denatured IgG and does not recognize denatured IgG. Conformation-specific secondary antibodies target spatial epitopes. When antibodies are denatured by high temperatures, they lose their native conformation and are no longer recognized by such antibodies-neither the heavy chain nor the light chain is detected. This effectively avoids interference from the heavy chain (55 kDa) and light chain (25 kDa) in immunoprecipitation (IP) experiments.
Formel:
(Gene_ID)(Accession)
Antibody Type:
Secondary Antibody
Anwendungsbeschreibung:
MCE Product type: Antibodies
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