Lorukafusp alfa, CAS [[2131168-99-3]]

Artikelnummer: MCE-HY-P990076
Artikelname: Lorukafusp alfa, CAS [[2131168-99-3]]
Artikelnummer: MCE-HY-P990076
Hersteller Artikelnummer: HY-P990076
Alternativnummer: MCE-HY-P990076-1MG,MCE-HY-P990076-5MG,MCE-HY-P990076-10MG
Hersteller: MedchemExpress
Kategorie: Antikörper
Alternative Synonym: APN-301, hu14.18-IL2, EMD 273063
Lorukafusp alfa (14.18 mAb, hu14.18-IL2) is an immunocytokine consisting of the humanized 14.18 anti-GD2 mAb linked to IL210. Lorukafusp alfa has activity mediated by activation of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity via the binding of hu14.18-IL2 to GD2 on the tumor cell surface, followed by binding to Fc receptors on effector cells along with activation of NK and T cells via IL2 receptor binding. Lorukafusp alfa has anti-tumor activity[1].
Molekulargewicht: (175.6 kDa)
Reinheit: 97.8
CAS Nummer: [2131168-99-3]
Target-Kategorie: Others
Anwendungsbeschreibung: MCE Product type: Inhibitory Antibodies