Aducanumab (Mouse IGG2a) is a monoclonal antibody that selectively targets aggregated amyloid-beta (Abeta). The variable region of Aducanumab (Mouse IGG2a) is consistent with that of Aducanumab (HY-P9967), while the constant region is of Mouse IGG2a sequence. Aducanumab (Mouse IGG2a) has strong selectivity for Abeta fibrils with EC50s of >1 µM and 0.2 nM for monomeric Abeta1-40 and fibrillar Abeta1-42, respectively. Aducanumab (Mouse IGG2a) can be used for Alzheimers disease (AD) research[1].
Molekulargewicht:
(147.019 kDa)
Reinheit:
99
Target-Kategorie:
Amyloid-beta
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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