Efzofitimod is a splice variant of the aminoacyl-tRNA synthetase HARS1, which is fused with the Fc segment of a human antibody. Efzofitimod targets the neuronal phospholipid NRP2 (neuropilin-2) and has anti-inflammatory and immunomodulatory activities. Efzofitimod can downregulate the innate and adaptive immune responses in inflammatory disease states, suppressing indirect lung disease (ILD)[1].
Molekulargewicht:
(64.54 kDa)
Reinheit:
99.29
CAS Nummer:
[2566615-11-8]
Target-Kategorie:
Aminoacyl-tRNA Synthetase
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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