Atrosimab is an Fv-Fc1K fusion protein with an EC50 value of 0.37 nM against humans. Atrosimab inhibits TNF-induced TNFR1 activation, release of IL-6 and IL-8, and cell death, and alleviates neuroinflammation. Atrosimab is applicable to research related to inflammatory diseases, neurodegenerative diseases, acute and chronic inflammation, experimental arthritis, non-alcoholic steatohepatitis, and experimental autoimmune encephalomyelitis[1][2][3].
Molekulargewicht:
(72.338 kDa)
Reinheit:
99
Target-Kategorie:
TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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