Inebilizumab (FUT8-KO) is an anti-CD19 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody.Inebilizumab (FUT8-KO) exhibits enhanced ADCC against B cells and can be used for research on multiple sclerosis and neuromyelitis optica[1][2].
Molekulargewicht:
(146.3 kDa)
Reinheit:
97
Target-Kategorie:
CD19
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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