Ivuxolimab is a fully human IgG2 agonist targeting OX40 (CD134), which selectively binds to the OX40 receptor on the surface of activated CD4+ and CD8+ T cells without inducing antibody-dependent cytotoxicity. Ivuxolimab can promote T cell proliferation, survival and cytokine (such as IFN-gamma, IL-2) secretion, inhibit regulatory T cell function, and enhance anti-tumor immune response. Ivuxolimab can be used in the study of melanoma, hepatocellular carcinoma, head and neck squamous cell carcinoma, etc[1][2][3].
Molekulargewicht:
(142.72 kDa)
Reinheit:
99.90
CAS Nummer:
[2128729-41-7]
Target-Kategorie:
Interleukin Related
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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