Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas[1].
Molekulargewicht:
(146.16 kDa)
Reinheit:
98.08
CAS Nummer:
[2226775-26-2]
Target-Kategorie:
TAM Receptor
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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