Brelovitug (BJT-778) is a humanized IgG1 neutralizing monoclonal antibody targeting hepatitis B surface antigen (HBsAg). Brelovitug binds with high affinity to HBsAg purified from HBV serotypes ad and ay, with Kd values of 0.22 nM and 0.39 nM, respectively. Brelovitug binds with high affinity to HBsAg of HBV genotypes A, B, C and D, with IC50 values of 0.07, 0.02, 0.02 and 0.07 nM, respectively. Brelovitug can be used in research related to chronic hepatitis B and chronic hepatitis D[1].
Molekulargewicht:
(143.954 kDa)
Reinheit:
99
CAS Nummer:
[3033337-14-0]
Target-Kategorie:
HBV
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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