IT1208 is a humanized anti-CD4 monoclonal IgG1 antibody. IT1208 features a defucosylated Fc region and markedly enhances antibody-dependent cellular cytotoxicity (ADCC). IT1208 depletes CD4+ T cells with a manageable safety profile in vivo. IT1208 can be used for colon cancer research[1][2].
Target-Kategorie:
Transmembrane Glycoprotein
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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