MEDI-1341 (TAK-341) is a blood-brain barrier-penetrant anti-alpha-synuclein monoclonal antibody. MEDI-1341 binds to the C-terminal epitope of both monomeric and aggregated forms of alpha-synuclein, penetrates the blood-brain barrier, reduces levels of free extracellular alpha-synuclein in cerebrospinal fluid (CSF) and brain interstitial fluid, and inhibits the cell-to-cell transmission of preformed alpha-synuclein fibrils. MEDI-1341 is applicable for research on Parkinsons disease [1] [2].
Target-Kategorie:
alpha-synuclein
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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