SAR 256212, MM 121, Anti-Human ERBB3/ErbB 3 Recombinant Antibody
Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models[1].
Molekulargewicht:
(143.14 kDa)
Reinheit:
96.043
CAS Nummer:
[1334296-12-6]
Target-Kategorie:
Apoptosis,EGFR
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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