Sirukumab (CNTO-136) is a humanized monoclonal anti-IL6 (Interleukin Related) IgG1kappa antibody. Sirukumab binds to IL6, preventing IL6-mediated signal transduction and activation of transcriptional activators, thereby blocking the downstream biological effects of IL6. Sirukumab can be used in the study of active lupus nephritis and rheumatoid arthritis[1][2].
Molekulargewicht:
(144.58 kDa)
Reinheit:
96.83
CAS Nummer:
[1194585-53-9]
Target-Kategorie:
Interleukin Related
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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