Tepoditamab, CAS [[2044679-53-8]]

Produktübersicht

• Artikelname: Tepoditamab, CAS [[2044679-53-8]]
• Artikelnummer: MCE-HY-P99390
• Hersteller Artikelnummer: HY-P99390
• Alternativnummer: MCE-HY-P99390-5MG,MCE-HY-P99390-1MG
• Hersteller: MedchemExpress
• Kategorie: Antikörper
• Alternative Synonym: MCLA 117

Produktbeschreibung

Tepoditamab (MCLA-117) is a full-length human IgG1 bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells. Tepoditamab induces upto 30-fold T-cell expansion. Tepoditamab results in moderate to strong cytokine (IFNgamma, IL-6, IL-8, IL-10, and TNFalpha) and IFNgamma release in human whole blood and PBMC, respectively. Tepoditamab can be used in acute myeloid leukaemia (AML) research[1][2][3].

Produkteigenschaften

• Molekulargewicht: (144.787 kDa)
• Reinheit: 99
• CAS Nummer: [2044679-53-8]
• Target-Kategorie: CD3,IFNAR,Interleukin Related,TNF Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Inhibitory Antibodies