Petosemtamab (FUT8-KO)

Produktübersicht

• Artikelname: Petosemtamab (FUT8-KO)
• Artikelnummer: MCE-HY-P99406A
• Hersteller Artikelnummer: HY-P99406A
• Alternativnummer: MCE-HY-P99406A-1MG,MCE-HY-P99406A-5MG,MCE-HY-P99406A-10MG
• Hersteller: MedchemExpress
• Kategorie: Antikörper

Produktbeschreibung

Petosemtamab (FUT8-KO) is an anti-EGFR and anti-LGR5 monoclonal antibody expressed in CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucosyl loss enhances the ADCC effect of the antibody. Petosemtamab (FUT8-KO) leads to EGFR signaling blockade and receptor degradation in LGR5+ cancer cells. Petosemtamab (FUT8-KO) can be used for research on solid tumors such as head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC)[1][2].

Produkteigenschaften

• Molekulargewicht: (145.5 kDa)
• Reinheit: 99
• Target-Kategorie: EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Inhibitory Antibodies