Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.
Molekulargewicht:
149000 (average)
Reinheit:
99.40
CAS Nummer:
[2407465-18-1]
Target-Kategorie:
Antibody-Drug Conjugates (ADCs)
Anwendungsbeschreibung:
ADC Related
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