AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs), with Kds of 2 nM, 2 nM, and 3 nM for RARalpha, RARbeta, and RARgamma, respectively. AGN 193109 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity.
Molekulargewicht:
392.49
CAS Nummer:
[171746-21-7]
Formel:
C28H24O2
Target-Kategorie:
RAR/RXR
Anwendungsbeschreibung:
MCE Product type: Reference Standards
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